Rats can predict aversiveness of Active Pharmaceutical Ingredients

Recrystallization of Active Pharmaceutical Ingredients

Quantitative analysis of active pharmaceutical ingredients (APIs)

Determination of pKa values of active pharmaceutical ingredients

The acid dissociation constant is an important physicochemical parameter of a substance, and knowledge of it is of fundamental importance in a wide range of applications and research areas. We present a critical review of published methods and approaches for the determination of acid dissociation constants, with a special emphasis on the pKa values of active pharmaceutical ingredients. a 2007 E...

From Form to Function: Crystallization of Active Pharmaceutical Ingredients

S ince the introduction of aspirin in 1899, and more particularly since the advent of antibiotic ‘‘wonder drugs’’ in the 1940s, society has come to rely on the widespread availability of therapeutic drugs at reasonable prices. It was a tremendous challenge to bring penicillin to market and could not have been done without the simultaneous development of both product and process under the inspir...

Flow reactor networks for integrated synthesis of active pharmaceutical ingredients

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